Browsing by Author "Ersan, Serpil"
Now showing items 1-11 of 11
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The Association of Plasminogen Activator Inhibitor Type 1 (PAI-1) Level and PAI-1 4G/5G Gene Polymorphism with the Formation and the Grade of Endometrial Cancer
Yildirim, Malik Ejder; Karakus, Savas; Kurtulgan, Hande Kucuk; Kilicgun, Hasan; Ersan, Serpil; Bakir, Sevtap (SPRINGER/PLENUM PUBLISHERS, 2017)Plasminogen activator inhibitor type 1 (PAI-1) is a serine protease inhibitor (Serpine 1), and it inhibits both tissue plasminogen activator and urokinase plasminogen activator which are important in fibrinolysis. We aimed ... -
Asymmetric dimethylarginine and M30 concentrations in heart failure
Dogan, Halef Okan; Beton, Osman; Ulger, Dilara; Ersan, Serpil; Bakir, Deniz (DERMAN MEDICAL PUBL, 2017)Aim: Apoptosis has been implicated in the development of various cardiovascular diseases. Caspase-cleaved cytokeratin 18 (M30) is released during apoptotic cell death. The concentrations of M30 and the correlation with ... -
Effects of cement dust exposure on malonyldialdehyde levels and catalaze activities in red blood cells
Nur, Naim; Yilmaz, Abduelkerim; Ersan, Serpil; Gueler, Nuran; Suemer, Haldun; Bakir, Sevtap (ASIAN JOURNAL OF CHEMISTRY, 2008)This study was designed to investigate the plasma oxidant and antioxidant status in both cement plant workers and control subjects. Malonyldialdehyde (MDA) levels and catalaze (CAT) activity were investigated for 42 cement ... -
Examination of free radical metabolism and antioxidant defence system elements in patients with obsessive-compulsive disorder
Ersan, Serpil; Bakir, Sevtap; Ersan, E. Erdal; Dogan, Orhan (PERGAMON-ELSEVIER SCIENCE LTD, 2006)Free radicals and oxidative stress are involved in the pathogenesis of various diseases. Malondialdehyde (MDA) is a natural product of lipid peroxidation in all mammalian cells. Vitamins C and E are nonenzymatic antioxidant ... -
Increased Irisin Concentrations in Patients with Crimean-Congo Hemorrhagic Fever
Buyuktuna, Seyit Ali; Dogan, Halef Okan; Bakir, Deniz; Ersan, Serpil; Koc, Derya; Bakir, Sevtap (NATL INST INFECTIOUS DISEASES, 2017)Crimean -Congo Hemorrhagic Fever (CCHF) is a life-threatening viral infection. The pathogenesis of the disease is not well understood. The aim of this study was to determine the change in irisin concentrations in patients ... -
Presepsin Levels of Patients with Crimean-Congo Hemorrhagic Fever
Demirpence, Ozlem; Dogan, Halef Okan; Ersan, Serpil; Sahin, Mehtap; Sahin, Hasan; Bakir, Mehmet (NATL INST INFECTIOUS DISEASES, 2016)Levels of presepsin (a soluble cluster of differentiation subtype 14 [CD14]) are thought to increase in cases of bacterial infection. CD14 has also been found to play a role in the pathogenesis of various viral diseases. ... -
Prostaglandin metabolite levels in patients with schizophrenia
Ersan, E. Erdal; Ersan, Serpil; Dogan, Orhan (CUMHURIYET UNIV TIP FAK PSIKIYATRI ANABILIM DALI, 2011)Objective: Schizophrenia is a neuropsychiatric disease which affects individuals, family members and society. Although many studies have been carried out on the etiopathogenesis of schizophrenia, the condition is not ... -
Role of MTHFR gene polymorphisms, serum tissue inhibitor of metalloproteinases-1, thymus chemokine-1 and thrombospondin-1 in endometrial cancer
Yildirim, Malik Ejder; Kilicgun, Hasan; Kurtulgan, Hande Kucuk; Karakus, Savas; Ersan, Serpil; Bakir, Sevtap; Sezgin, Ilhan (E-CENTURY PUBLISHING CORP, 2016)The aim of this study was to evaluate the relationship between the MTHFR gene variants (677 C -> T and 1298 A -> C), serum tissue metalloproteinases inhibitor (TIMP-1), thrombospondin-1 (TSP-1), thymus chemokine-1 (TCK-1) ... -
Serum selenium and plasma malondialdehyde levels and antioxidant enzyme activities in patients with obsessive-compulsive disorder
Ozdemir, Ercan; Cetinkaya, Sevil; Ersan, Serpil; Kucukosman, Seda; Ersan, E. Erdal (PERGAMON-ELSEVIER SCIENCE LTD, 2009)There is mounting evidence indicating that reactive free radical species are involved in initiation and development of many different forms of human pathologies including psychiatric disorders. In the present study, we ... -
Thiol Disulfide Homeostasis in Schizophrenic Patients Using Atypical Antipsychotic Drugs
Dogan, Halef Okan; Ersan, Etem Erdal; Aydin, Huseyin; Erdogan, Serpil; Ersan, Serpil; Alisik, Murat; Bakir, Sevtap; Erel, Ozcan; Koc, Derya (KOREAN COLL NEUROPSYCHOPHARMACOLOGY, 2018)Objective: Schizophrenia is a severe, debilitating mental disorder characterized by behavioral abnormalities. Although several studies have investigated the role of oxidative stress and the effects of antipsychotic drugs ... -
Xanthine oxidase, adenosine deaminase and vitamin E levels in patients with schizophrenia
Kilicgun, Hasan; Ersan, Etem Erdal; Bakir, Sevtap; Ersan, Serpil; Koc, Derya; Demirpence, Ozlem; Dogan, Kubra (CUMHURIYET UNIV TIP FAK PSIKIYATRI ANABILIM DALI, 2016)Objective: Neuronal damage caused by free radicals is believed to be effective in pathogenesis of several psychiatric disorders. This belief is due to the toxic effects of free radicals that play a role in oxidative stress. ...